Anti-Pyruvate Dehydrogenase E1 alpha antibody GTX104015 from GeneTex

Product Specs
ItemAnti-Pyruvate Dehydrogenase E1 alpha antibody
CompanyGeneTex
Price Pricing Info Supplier Page
Catalog NumberGTX104015
Quantity100 µl
ApplicationsWB, ICC/IF, IHC-P, IHC-Wm, IP, IHC (Free Floating)
Concentration1.39mg/ml
Conjugate/TagUnconjugated
PurityPurified by antigen-affinity chromatography
ReactivityHuman, Mouse, Rat, Zebrafish
TargetPyruvate Dehydrogenase E1 alpha
IsotypeIgG
HostRabbit
Antibody TypePrimary Antibodies
ImmunogenRecombinant protein encompassing a sequence within the center region of human Pyruvate Dehydrogenase E1 alpha. The exact sequence is proprietary
NCBI Full Gene Namepyruvate dehydrogenase E1 alpha 1 subunit
NCBI Gene Aliasespyruvate dehydrogenase E1 alpha 1 subunit, PDHA, PDHAD, PDHCE1A, PHE1A, PHE1A, PDHCE1A, E1alpha, PDHAD, PDHA
ClonalityPolyclonal
FormatPBS, 20% Glycerol, 0.025% ProClin 300
Research AreaMetabolism, Organelle Markers
Gene NamePDHA1
Molecular Weight43

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

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Website: http://www.genetex.com

(1) Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivoPLOS ONENovember 30, 2023Collin M. MacLeod, Fawad A. K. Yousufzai, Liam T. Spencer, Sarah Kim, Lucianne A. Rivera-Rosario, Zerian D. Barrera, Lindsay Walsh, Claude Krummenacher, Benjamin Carone, Ileana Sotocerebellar organotypic slices were rabbit anti-pyruvate dehydrogenase E 1 alpha (PDHE1) (1:200, GeneTex, # GTX104015), rabbit anti-TFEB (1:200, Bethyl Laboratories, A303-673A), LAMP1 (1:200, BioLegend, 121602) and mouse

(2) Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C diseaseScientific ReportsApril 6, 2023Sarah Kim, Kathleen Ochoa, Sierra E. Melli, Fawad A. K. Yousufzai, Zerian D. Barrera, Aela A. Williams, Gianna McIntyre, Esteban Delgado, James N. Bolish, Collin M. Macleod, et al.(1:200, Cell Signaling, #3180), rabbit anti-pyruvate dehydrogenase E 1 alpha (PDE) (1:200, GeneTex, # GTX104015), rat anti-CD107a (LAMP-1) (1:200, BioLegend, # 121602). Microscopy image analysis For all the image

(3) A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phaseDevelopmental cellJuly 25, 2022Kirova DG, Judasova K, Vorhauser J, Zerjatke T, Leung JK, Glauche I, Mansfeld J.2947; RRID: AB_823586 PARP,Cell Signaling Technology,Cat# 9542; RRID: AB_2160739 PDHA,GeneTex,Cat# GTX104015; RRID: AB_1951155 PDHB,GeneTex,Cat# GTX119625; RRID: AB_11163683 RPL26,Bethyl,Cat# A300-686A; RRID:

(4) Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissueCell metabolismApril 5, 2022Rosina M, Ceci V, Turchi R, Chuan L, Borcherding N, Sciarretta F, Sánchez-Díaz M, Tortolici F, Karlinsey K, Chiurchiù V, et al.Abcam); anti-ACO2 (sc-130677, Santa Cruz Biotechnology); anti-ACAA2 (GTX115417, GeneTex); anti-PDHα (GTX104015, GeneTex); anti-NOS2 (ab205529, Abcam); anti-PINK1 (sc-517353, Santa Cruz Biotechnology); anti-ACTIN

(5) Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodelingCell death & diseaseOctober 20, 2020Zhang R, Shen W, Du J, Gillies MC.ab101456",Rabbit,1:2000,1:200 OGDH,"Sigma, HAP020347",Rabbit,–,1:200 OGDH,"Thermo Scientific, PA5-28195",Rabbit,1:2000,– PDHE1α,"GeneTex, GTX104015",Rabbit,1:2000,1:200 PKM2,"Cell Signaling, CST#4053",Rabbit,1:2000,1:200 p-PKM2Tyr105,"Cell Signaling,

(6) Mitochondrial RNA granules are fluid condensates positioned by membrane dynamicsNature cell biologyOctober 1, 2020Rey T, Zaganelli S, Cuillery E, Vartholomaiou E, Croisier M, Martinou JC, Manley S.anti-OxPhos Complex IV subunit IV (clone 20E8C12,Thermo Fisher Scientific, A21348), anti-PDHE1α (GeneTex, GTX104015). All primary antibodies were diluted 1:2000. STED microscopy STED microscopy was performed on a Leica

(7) Thiamine mimetics sulbutiamine and benfotiamine as a nutraceutical approach to anticancer therapyBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJanuary 1, 2020Jonus HC, Byrnes CC, Kim J, Valle ML, Bartlett MG, Said HM, Zastre JA.

(8) Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus VulgarisThe Journal of biological chemistrySeptember 25, 2015Chen Y, Chernyavsky A, Webber RJ, Grando SA, Wang PH.

(9) Protein kinase B (PKB/AKT1) formed signaling complexes with mitochondrial proteins and prevented glycolytic energy dysfunction in cultured cardiomyocytes during ischemia-reperfusion injuryEndocrinologyMay 1, 2014Deng W, Leu HB, Chen Y, Chen YH, Epperson CM, Juang C, Wang PH.

(10) Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilizationJournal of lipid researchDecember 1, 2012Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, et al.Antibody dilutions are as follows: PDH-E1α (pSer293) 1:10,000 (AP1062; Calbiochem), PDH-E1α 1:50,000 (GTX104015; GeneTex), Ppp1r1a 1:50,000 (ab40877, ABCAM), porin 1:2,000 (MSA03; MitoSciences), fission1 (Fis1) 1:5,000

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Anti-Pyruvate Dehydrogenase E1 alpha antibody

Anti-Pyruvate Dehydrogenase E1 alpha antibody

Anti-Pyruvate Dehydrogenase E1 alpha antibody from GeneTex

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GeneTex

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Anti-Pyruvate Dehydrogenase E1 alpha antibody from GeneTex

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